Funding
Publications Associated with P&F Funding
Current or Past Recipients
Funding Application Information
ADDITIONAL REQUIREMENTS
DIRECTIONS TO START THE APPLICATION PROCESS for Type A or Type B P&F Proposals
1. Check guidelines for eligibility
a. Priority will be given to Junior Investigators and Postdocs.
b. Established Investigators starting a new line of Research in nonmalignant hematology - cannot be focused on currently funded project.
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Current P&F Projects
Title | PI, Key Personnel, Mentor, etc. | Investigator Institutions | Center/Core(s) to Be Used | At Center/Core Institutions | Award Type | Award Year |
---|---|---|---|---|---|---|
Generation of conditional Runx1 mutant mouse strains to delineate Runx1 roles in | Vikram R Paralkar, MD | University of Pennsylvania Perelman School of Medicine | Mouse | Boston Children's Hospital | Type A | 2021 |
Characterization of the hematopoietic system and the contribution of myeloid cells to mortality in the COVID-19 mouse model | Ushashi Dadwal, PhD | Indiana University School of Medicine | Flow Cytometry | Indiana University School of Medicine | Type A | 2021 |
3D tissue cytometry of the unperturbed hematopoietic niche to study the spatial relationship between its different components | Edward Srour, PhD and Roy El Koussa, MD | Indiana University School of Medicine, Purdue University | Optical Microscopy Core | Indiana University School of Medicine | Type A | 2021 |
Generation of a zebrafish model of Congenital Dyserythropoietic Anemia-1 | Gary M Kupfer, MD and Susree Modepalli, PhD | Georgetown University | Zebrafish Core | Boston Children's Hospital | Type A | 2021 |
The role of HMGA1 in Pathologic Cytokine Signaling in Myeloproliferative Neoplasms | Jung-Hyun Kim, PhD | Johns Hopkins University School of Medicine | Cell Preparation and Analysis | Yale University | Type A | 2021 |
Iron deficiency in preterm neonates: prevalence, surveillance, contributing factors | Timothy Marvin Bahr, MS, MD | University of Utah School of Medicine | Iron and Heme, Metabolomics | University of Utah | Type B | 2021 |
Preventing HSC functional decline by sustaining linker histone expression | Kutay Karatepe, PhD | Yale University | Imaging Core | Yale University | Type B | 2021 |
Selective activity of selinexor, eltanexor and sunitinib in TET2-mutant cases | Nicole Prutsch, PhD | Dana-Farber Cancer Institute | Animal Modeling and Flow Cytometry | Yale University | Type B | 2021 |
Investigations of hepatic heme homeostatic mechanisms using ALAS-deficient mice | Makiko Yasuda, MD, PhD | Icahn School of Medicine at Mt Sinai | Iron and Heme | University of Utah | Type B | 2021 |
Role of Mitoferrin-1 isoforms and intron retention in iron homeostasis and mitochondrial biology | Prajwal C. Boddu, MD | Yale University School of Medicine | Cell Prep and Analysis, Iron and Heme | Yale University, University of Utah | Type B | 2021 |
Single cell resolution of epigenetic regulatory events in human hematopoietic stem and progenitor cells | Patrick Paddison, PhD | Fred Hutchinson Cancer Research Center | Hematopoietic Cell Processing and Repository Core | Fred Hutchinson Cancer Research Center | Type B | 2021 |
Identifying and exploiting metabolic vulnerabilities to prevent clonal hematopoiesis | Brandon Ghelier, PhD | Boston Children’s Hospital | Metabolomics, Zebrafish, Flow Cytometry | University of Utah, Boston Children’s Hospital | Type B | 2021 |
The Roles and Regulation of Iron Regulatory Proteins 1 and 2 During Cellular Ferroptosis | McKale Montgomery, PhD | Oklahoma State University, Stillwater | Iron and Heme, Mutation Generation & Detection | University of Utah | Type A | 2021 |
Investigating the role of novel genes in hematopoietic stem cell development using CRISPR/Cas9 gene knockout in a vascular niche model in vitro | Adam Heck, PhD and Brandon Hadland, MD, PhD | Fred Hutchinson Cancer Research Center | Vector Production | Fred Hutchinson Cancer Research Center | Type A | 2021 |
Optogenetic stimulation of bone marrow adrenergic nerves | Christa Haase, PhD | Massachusetts General Hospital Charles P Lin Lab | N/A | Boston Children's Hospital/Harvard | Type B | 2021 |
Erythroblastic Island Heme Synthesis under Normal and Inflammatory Conditions | Amy Medlock, PhD | University of Georgia | Targeted Cell Procurement and Processing Services | Fred Hutchison Cancer Research Center | Type B | 2021 |
Quantification of total protoporphyrins and heme levels, and ALAS activity in novel mouse models of X-Linked Sideroblastic Anemia and X-linked Protoporphyria | Sarah DuCamp, PhD | Boston Children's Hospital/Harvard | Iron and Heme Core | University of Utah | Type A | 2021 |
Identification of pregnancy-related regulators of hepcidin | Veena Sangkhae, PhD | UCLA David Geffen School of Medicine | Mutation Generation and Detection Core | University of Utah | Type B | 2021 |
Oct1/Pou2f1 role in human blood cell development | Jelena Perovanovic, PhD | University of Utah School of Medicine | Mutation Generation and Detection Core | University of Utah | Type A | 2021 |
Dissecting the mechanicsms underlying transcriptional dysregulation in MDS | Elizabeth Bonner, BS | Fred Hutchinson Cancer Research Center | Specialized Mouse Services, Cell Procurement | Fred Hutchinson Cancer Research Center | Type A | 2021 |
Biomolecular condensates in splicing factor-mutant myelodysplastic syndromes | Giulia Biancon PhD | Yale School of Medicine | Imaging, Cell Prep, FACSorting | Yale University | Type B | 2021 |
VPS4A/ESCRT-III and endosomal trafficking in terminal erythropoiesis | Katie Seu PhD | Cincinnati Children's Hospital | Single Cell Characterization and Procurement Core | Cincinnati University | Type B | 2021 |
Developing low-cost, multiplexed nanoscale imaging tools for hematology specimens | Yongxin Zhao PhD | Carnegie Mellon University | N/A | Yale University | Type B | 2021 |
Control of Alas2 expression by Iron Regulatory Proteins during normal and pathological erythropoiesis | Sarah DuCamp, PhD | Boston Children's Hospital/Harvard | Iron and Heme | University of Utah | Type B | 2021 |
Investigation of RBM15 and the m6A epitranscriptome in megakaryopoiesis | Madeline Mayday, BS | Yale School of Medicine | N/A | Yale University | Type B | 2022 |
TERT Splice Variants and Myelopoiesis in Diabetic CD34+ cells | Yagna Prasada Rao Jarajapu, PhD | North Dakota State University | Experimental Mouse Model | Indiana University | Type B | 2022 |
Novel mechanisms of action of HFE in hepcidin and iron homeostasis regulation | Xia Xiao, PhD | Harvard Medical School | Bioinformatics | Cincinnati Children's | Type B | 2022 |
Fine-Tuning of Hemoglobinization Through Heme Import by Erythrocytic HRG1 | Audrey Belot, PhD | University of Maryland | Iron and Heme | University of Utah | Type B | 2022 |
Meet the Investigators
Get to know the investigators behind our current P&F projects. Click on an investigator's name to visit their website.
Vikram R Paralkar, MD
Ushashi Dadwal, PhD
Edward Srour, PhD & Roy El Koussa, MD
Gary M Kupfer, MD & Susree Modepalli, PhD
Sarah DuCamp, PhD
Katie Seu, PhD
Yongxin Zhao, PhD
Jung-Hyun Kim, PhD
Timothy Marvin Bahr, MS, MD
Kutay Karatepe, PhD
Nicole Prutsch, PhD
Christa Haase, PhD
Veena Sangkhae, PhD
Jelena Perovanovic, PhD
Makiko Yasuda, MD, PhD
Prajwal C Boddu, MD
Patrick Paddison, PhD
Brandon Ghelier, PhD
Amy Medlock, PhD
Giulia Biancon, PhD
Elizabeth Bonner, BS
Madeline Mayday, BS
Yagna Prasada Rao Jarajapu, PhD
Xia Xiao, PhD
Audrey Belot, PhD