Funding

Funding Opportunities

The CCEH program supports pilot and feasibility program grants funding small projects aimed to at generating preliminary data for inclusion in larger grant applications as well as short-term enrichment activities to learn new techniques. The grants will be awarded competitively and are designed to support collaborative research projects that utilize core resources at one of the five CCEH centers.

Current P&F Projects

Title PI, Key Personnel, Mentor, etc. Investigator Institutions Center/Core(s) to Be Used At Center/Core Institutions
Resolving a controversy about the bone marrow hematopoietic niche Konstantinos Kokkaliaris, PI; David T. Scadden, mentor Harvard Viral Vectors & Gene Editing Tools (Hutch); Mouse Embryonic Stem (ES) Cell and Gene Targeting Core (Boston) Fred Hutch, Boston Children's Hospital
Modeling a-thalassemia using hiPSCs to investigate the role of telomere cohesion on aglobin expression Mahesh Ramamoorthy and Merlin Nithya Gnanapragasam, MPI; Cleveland State University Stem Cell Core Facility Boston Children's Hospital
HMGA1 Chromatin Regulators in Regenerative Capacity of Human Hematopoietic Stem Cells Linda M. S. Resar, PI Johns Hopkins University School of Medicine Engineering of primary human CD34+ cells Yale University
The Role of Intercellular Communication between Bone Marrow Niche Cells and Megakaryocytic-Erythroid Progenitors Vanessa Scanlon, Pi;  Beverly Torok-Storb and Diane Krause, Mentors Yale University Hematopoietic Cell Procurement and Processing Services Fred Hutch
Evaluating Insulin-Like Growth Factor-1 (IGF1) As a Targetable Mechanism to Rescue Human Hematopoietic Stem Cell Aging Jennifer J. Trowbridge, PI JAX Hematopoietic Cell Procurement and Processing Services Fred Hutch
Characterization of macrophage immune-metabolic skewing induced by heme, iron and erythrophagocytosis Francesca Vinchi, PI NY Blood Center Metabolomics Core University of Utah
The role of the reductases Lcytb and Steap3 in lysosomal iron recycling in macrophages Diane M Ward, PI University of Utah School of Medicine Metabolomics and Iron and Heme Cores University of Utah
Metabolomic Investigation of Mitochondrial Heme Metabolon Proteins Amy E. Medlock, PI University of Georgia, Augusta University/University of Georgia Medical Partnership Metabolomics, Iron and Heme, and MGD Cores University of Utah

To read the abstracts for these projects, please click here.

Meet the Investigators

Get to know the investigators behind our current P&F projects. Click on an investigator's name to visit their website.

P&F at the Utah CIHD