The Experimental Mouse Resources Core (EMRC) of the Cooperative Center of Excellence in Hematology is used by investigators for in vivo studies focused molecular and cellular mechanisms involved in steady state hematopoiesis, the bone marrow niche, bone marrow transplantation, and immune cell function.
Centralization of these services prevents duplication of resources, ensures consistent supply of acclimated mice, and maintains high quality research infrastructure essential for conducting in vivo studies of hematopoietic stem and progenitor cell (HSPC) function. The core provide CCEH investigators advanced resources for their studies using mice for murine and human transplantation models.
• Maintain on-site breeding colonies of essential mice to study human and murine hematopoiesis in vivo.
• Provide specialized core services and consultation to CCEH investigators.
• Serve as an educational resource for CCE laboratories.
• Work in concert with other CCEH centers and investigators nationwide