Project TitlePIInvestigator InstitutionCCEH CenterCore UtilizedAward TypeYearhf:tax:cceh-centerhf:tax:pf-project-year
CODEX-based spatial imaging of Rap1A/B-deficient osteoblast niches and hematopoietic dysregulationRahul S. Kanumuri, Ph.D.Indiana University, School of Medicine, Indianapolis
Flow & Tissue Cytometry Core
Type A2026indiana2026
Regulation of hematopoietic stem cell (HSC) proliferation by Epithelial Growth Factor Like-7 (EGFL7)Chinmayee Goda, PhDHuntsman Cancer Institute, University of Utah
Hematopoietic Cell Procurement & Processing
Type A2026fred-hutch2026
Adapting Phenocycler 2.0TM to Image Mitochondria in the Hematopoietic Niche of the Murine Bone MarrowDavid L. Waning, PhDIndiana University
Flow & Tissue Cytometry Core
Type A2025indiana2025
Modeling splicing factor mutations in human hematopoiesis using AAV6-based gene editing technologyElana Thieme, BSFred Hutch Cancer Center
Cell Manipulations Tools Core | Vector Production
Type A2025fred-hutch2025
Interplay of RNA methylation and transcription elongation during human erythropoiesisKaustav Mukherjee, PhDMount Sinai, School of Medicine
Cell Preparation & Analysis Core
Type A2025yale2025
Metabolic Determinants of In Vitro HematopoiesisRong Qiu, MD, PhDChildren's Hospital of Philadelphia
Metabolomics | Proteomics and Mass Spectrometry Core
Type A2025utah2025
Uncovering the Spatial Architecture of Hematopoietic and Mesenchymal Niches During Fracture Healing Using CODEX ImagingDeepak Kumar Khajuria, PhDIndiana University
Flow & Tissue Cytometry Core
Type A2025indiana2025
Purifying the syndecan-2 bone marrow interactomeKayleigh Robichaux, PhDFred Hutch Cancer Center
Cell Manipulations Tools Core | Vector Production
Type A2025fred-hutch2025
Nuclear envelope protein emerin regulates structure and function of the erythrocyte membraneBrendan J. O'Brien, PhDYale University
Yale Imaging Core, Cell Preparation & Analysis Core
Type A2025yale2025
Investigating metabolite-driven regulation of calreticulinNicole ArellanoUniversity of Utah
Protein-Metabolite Discovery Core
Type A2025utah2025
Training a machine learning model to identify long-term engrafting HSCsHelong Gary Zhao, PhDFred Hutchinson Cancer Center
Hematopoietic Cell Procurement & Processing
Type A2024fred-hutch2024
Fine-Tuning of Hemoglobinization Through Heme Import by Erythrocytic HRG1Audrey Belot, PhDUniversity of Maryland
Iron and Heme Core Facility
Type B2022utah2022
Novel mechanisms of action of HFE in hepcidin and iron homeostasis regulationXia Xiao, PhDMass General Hospital/Harvard Medical School
Bioinformatics Core
Type B2022cincinnati2022
TERT Splice Variants and Myelopoiesis in Diabetic CD34+ cellsYagna Prasada Rao Jarajapu, PhDNorth Dakota State University
Experimental Mouse Resources Core
Type B2022indiana2022
Investigation of RBM15 and the m6A epitranscriptome in megakaryopoiesisMadeline Mayday, BSYale School of Medicine
N/A
Type B2022yale2022
Iron-Regulatory Protein 2 Phosphorylation Regulation of ErythropoiesisElizabeth Leibold, PhDUniversity of Utah School of Medicine
Iron and Heme Core Facility
Type A2022utah2022
Adapting multiplexed high-resolution imaging to investigate the hematopoietic niche of bone marrowSonali J. Karnik, PhDIndiana University School of Medicine
Flow & Tissue Cytometry Core
Type A2022indiana2022
Targeting fatty acid oxidation to expand hematopoietic stem cellsPeter S Klein, MD, PhDUniversity of Pennsylvania School of Medicine
Hematopoietic Cell Procurement & Processing
Type B20222022
Driving myeloid progenitor expansion with small moleculesStephen Maxwell Scalf, PhDYale School of Medicine
Cell Preparation & Analysis Core, Flow & Tissue Cytometry Core
Type B2022yale2022
Surprising activity of a small molecule compound on myeloid progenitorsShangqin Guo, PhDYale School of Medicine
Metabolomics Core Facility
Type A2023yale2023
HMGA1 in Cardiovascular Disease Associated with TET2 Mutant Clonal HematopoiesisZanshé Thompson, PhD Johns Hopkins School of Medicine
Cell Preparation & Analysis Core
Type A20232023
Understanding the exosomal communication of bone marrow stromal cells with hematopoietic stem and progenitor cellsReza Shahbazi, PhD Indiana University Simon Comprehensive Cancer Center
Cell Preparation & Analysis Core
Type A2023indiana2023
Developing an AAV-based gene editing tool to model aberrant RNA splicing in hematopoiesisSayantani Shinha, PhDFred Hutchinson/University of Washington
Vector Production Core
Type A2023fred-hutch2023
C-FiSHH – a CRISPR-based Functional in vivo Screen of Human HematopoiesisEmily Collins, PhDFred Hutchinson Cancer Center
Vector Core
Type B2023fred-hutch2023
Lipid perturbations in the red blood cell due to hypoxia, sickle cell disease and malaria infectionRadoslaw Omelianczyk, PhDUniversity of Utah School of Medicine
Metabolomics Core Facility
Type B2023utah2023
The function of ANKRD26 and its role in megakaryopoiesisLiang Zheng, PhDUniversity of Kansas Medical Center
Cell Preparation & Analysis Core
Type B2023yale2023
Multiplex imaging of the regenerating bone marrow microenvironmentChristina Termini, PhDFred Hutchinson Cancer Center
CODEX Imaging Core Indiana
Type A2023fred-hutch2023
Using a Novel CODEX Antibody Panel for Spatial Cellular Proteomics of the Bone Hematopoietic and Vascular Niches under Systemic Thrombopoietin TreatmentPatrick L. Mulcrone, PhDIndiana University School of Medicine
Flow & Tissue Cytometry Core
Type A2023indiana2023
Interactions between heme export and choline import via FLVCR1Janis Abkowitz, MDUniversity of Washington
Iron and Heme Core Facility, Metabolomics Core Facility
Type A2023utah2023
Investigating aging-related changes in the bone marrow matrix and hematopoietic stem cell niche using multiplexed spatial-resolution imagingMilos Marinkovic, PhDUniversity of Texas Health – San Antonio
Flow & Tissue Cytometry Core
Type A20232023
Intrinsic regulation of erythropoiesis by the cholesterol synthesis pathwayChristina Termini, PhDFred Hutchinson Cancer Center
Vector Core
Type B2023fred-hutch2023
Transcriptional Mechanisms that Accelerate Red Blood Cell Production in AnemiaKyle Hewitt, PhDUniversity of Nebraska School of Medicine
Fred Hutchinson CCEH Cell Production CD34+ Core
Type B20232023
Metabolic Changes in Erythroblasts from Iron-Regulatory Protein 2 Phosphorylation Mutant MiceElizabeth A. Leibold, PhDUniversity of Utah School of Medicine
Metabolomics Core Facility
Type A20242024
Metabolic determinants of MEP fate specificationRubia Isler Mancuso, PhDYale
Metabolomics Core Facility
Type A2024yale2024
Improving hematopoietic stem cell quantification in a sickle cell disease contextKim Vanuytsel, PhDBoston Medical Center
Cell Preparation & Analysis Core
Type B2024yale2024
Investigation of selective autophagy receptor optineurin in erythropoiesisMassiel Chavez Stolla, PhDUniversity of Washington School of Medicine
N/A
Type B20242024
Gene Expression Profiling to Predict Hematopoietic Cell Potency in TransplantationJames Ropa, PhDIndiana University School of Medicine,
IU-CCEH Flow Cytometry | Cincinnati Children’s CCEH DNA Sequencing Cores
Type B2024cincinnati indiana2024
The function of neutrophilic granule protein in hematopoietic developmentKostadin Pajcini, PhDUniversity of Illinois at Chicago
Xenotransplant and Genome Editing Core
Type A2024cincinnati2024
Critical Role of a SNP in the SENP1 gene regulation and excessive erythrocytosis at high altitude Priti Azad, Ph.D.University of California, San Diego
Cell Preparation & Analysis Core
Type A2024yale2024
Investigating Long-Term Genome Editing Safety in Hematopoietic Stem CellsPhillip A Doerfler, PhDVersiti Blood Research Institute
Hematopoietic Cell Procurement & Processing
Type A2024fred-hutch2024
Minimal manipulation of HPSCs and novel viral vectors for faster, efficient transduction of hematopoietic stem and progenitor cellsRachel Bakyayita Kyeyune, MBChB, PhDFred Hutchinson Cancer Center
Hematopoietic Cell Procurement & Processing
Type A2024fred-hutch2024
Changes in the bone marrow microenvironment in cystic fibrosisEmanuela Bruscia, PhDYale University School of Medicine
Flow & Tissue Cytometry Core
Type A2024indiana2024
Dissecting microenvironmental metabolic contributions to erythropoiesisMarlies P Rossman, PhDUniversity of Rochester
Single Cell Characterization and Procurement Core
Type B2024cincinnati2024
UPLC Analysis of Porphyrin Biochemistry in a Planarian Model of Acute PorphyriasJason Pellettieri, PhDBoston Children’s Hospital
Iron and Heme Core Facility
Type A2022utah2022
Engineering degron system in human CD34+ cells to study dosage effects of endogenous transcription factorsCharles Antony, PhDPerelman School of Medicine
Cell Preparation & Analysis Core
Type B20232023
Uncovering RNA isoform diversity and functionality in hematopoietic cell-fate determinationStanley Lee, PhDFred Hutchinson Cancer Center
N/A
Type B20242024
Regulation of hematopoietic stem cell quiescence by a proteoglycan proteinYoonA Kang, PhDWashington University School of Medicine
Hematopoietic Cell Procurement & Processing
Type B2024fred-hutch2024
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