Opportunities

Postdoctoral Associate
Trowbridge Lab
Bar Harbor, ME

A Postdoctoral Associate position is available in Dr. Jennifer Trowbridge’s laboratory at The Jackson Laboratory in Bar Harbor, Maine. The Trowbridge lab is dedicated to uncovering the fundamental mechanisms that govern hematopoietic stem cell (HSC) biology across three interconnected areas:

• HSC aging – both the cell-intrinsic changes that accumulate over a lifetime and alterations that occur in the bone marrow microenvironment where these cells reside
• Clonal hematopoiesis – understanding why somatic mutations in epigenetic regulatory genes (e.g., DNMT3A, TET2, ASXL1) are selectively expanded in HSCs with aging, and how they modify risk of aging-associated diseases
• Hematologic malignancies – the mechanisms by which clonal hematopoiesis progresses to myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML)

Our long-term goal is to identify intervention strategies that extend “healthspan” of blood stem cells – preserving their regenerative capacity into older age and reducing the risk of blood cancers.  The multi-disciplinary nature of our work is highlighted our recent publications in Nature Communications (Young et al., 2025) and Nature (Hosseini et al., 2025) identifying elevated mitochondrial metabolism as a selective dependency of CH-mutant HSCs.

The Trowbridge lab offers a highly collaborative environment with strong national and international collaborations. Past and current trainees have been extremely successful in obtaining competitive grant funding and fellowships, and have gone on to independent positions in both academia and industry.

Responsibilities

The successful candidate will be able to plan, develop, execute, and analyze an independent research project within one or more of the lab’s focus areas. Additional responsibilities include preparing manuscripts, fellowship applications, and conference presentations, mentoring junior lab members and contributing to a collaborative team environment.

Required Qualifications

• M.D. or Ph.D. in biological or related sciences
• Minimum of one first-author publication from graduate work
• Strong foundational training in molecular and cell biology
• Exceptional verbal and written communication skills
• Self-motivated and able to work independently as well as collaboratively

Preferred Qualifications

Experience or training in any of the following areas:

• Hematopoiesis, stem cell biology, aging, or immunology
• Epigenetics or chromatin biology
• Mouse HSC biology-related experimental techniques
• CRISPR-based approaches including gene editing in primary cells, sgRNA design, lentiviral delivery
• Computational biology/bioinformatics

How to Apply

A complete application must include a cover letter describing past research accomplishments, current research interests, and career aspirations; a current CV; and the names and contact information of three references.

JAX Salary

Year 0 – 1: $65,589

Year 1 – 2: $67,318

Year 2 – 3: $69,095

Year 3 – 4: $70,521

Year 4 – 5: $72,877

Year 5 – 6: $75,569

Based on years of experience as Postdoc

About JAX:

The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.

Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit www.jax.org​​​​​​​.

EEO Statement:

The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.

The Beaudin Lab in the Division of Hematology and Hematologic Malignancies at the Spencer Fox Eccles School of Medicine at the University of Utah is seeking  passionate, motivated, and qualified applicants for a postdoctoral position.  Our lab broadly investigates developmental origins of disease susceptibility at the interface of developmental hematopoiesis and developmental immunology,  We are seeking a PhD-level candidate with background and interest in developmental immunology and/or hematopoiesis, and additional expertise in mouse models, bioinformatic or multi-omic analysis, and human immunology would be highly desired.   Ability to work collaboratively with a highly engaged team is a must.  Interested candidates should contact Anna Beaudin (anna.beaudin@hsc.utah.edu) and submit materials online to: https://utah.peopleadmin.com/hr/postings/189683

The Jackson Laboratory (JAX), one of the world’s leading nonprofit biomedical research organizations, is at the forefront of genetic and genomic research. We are seeking accomplished faculty at all ranks to join our mission-driven research community that boasts a unique blend of dynamic and established scientists from around the world, united in pursuit of a common goal: to translate genetic discoveries into human health.

We seek candidates with creative ideas, an integrative perspective, novel technologies in their experimental approaches, and a collaborative spirit to address important problems in human health and disease.

Post/Doctoral position available at the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda MD, for a young researcher interested in joining a young and dynamic research group in mammalian iron metabolism, iron sulfur cofactors, iron related neurodegeneration, iron sulfur dependent viral replication, RNA protein interactions and systems biology analysis of iron regulation.

Terms: 24 months, with yearly extensions possible after initial contract. The NIH is dedicated to building an inclusive and diverse community in its training and employment programs.

DHHS, NIH, and NICHD are Equal Employment Opportunity Employers

For further information, contact: rouault@mail.nih.gov.

Postdoctoral Fellow to Elucidate Mechanisms of Ferroptosis

Seeking highly motivated candidates to perform mechanistic studies for the characterization of pathways involved in iron sensing and ferroptosis in cancer cells. PI Dr. Mei Koh’s lab at the University of Utah College of Pharmacy focuses on the identification of new therapeutic strategies that exploit the inflammatory and hypoxic tumor microenvironment within solid tumors. The funded project focuses on the role of Fe-S assembly proteins in driving kidney cancer and modulating sensitivity to ferroptosis.

Candidates must possess a PhD degree in biology, biochemistry, molecular pharmacology or related field. Candidates should have high proficiency in iron metabolism and in general cell biology and molecular biology techniques including cell culture, molecular cloning, western blots, PCR, and cell viability/reporter assays. Experience in cancer cell signaling is desirable but not essential. Experience in animal handling/surgery is desirable but not essential. Candidates should be organized, able to work independently and as part of a team in a highly collaborative research environment. Fluency in English is required. Candidates should be eligible to work in the USA.

Responsibilities include:

1) Perform laboratory experiments, which may include cell culture, molecular cloning, western blotting, PCR, animal handling/surgery, and protein purification.
2) Plan and execute experiments, perform data analysis, have ability to work independently and as part of a team.
3) Present data in group meetings, and at local and international meetings.
4) Contribute to general lab management including supervising lab technicians and students where necessary.
5) Prepare manuscripts.

The University of Utah and the Huntsman Cancer Institute:

Founded in 1850, The University of Utah (the U) is the flagship institution of higher learning in Utah, and offers over 100 undergraduate and more than 90 graduate degree programs to over 30,000 students. As a preeminent research and teaching institution, the University ranks among the top 50 U.S. universities by total research expenditures. Huntsman Cancer Institute (HCI) at the University of Utah is a nationally recognized research center and treatment hospital, and an NCI-designated Comprehensive Cancer Center. HCI and the U are located in Salt Lake City, a vibrant, increasingly diverse and family friendly city; nestled against the mountains of the Wasatch Front, which provide world class skiing, hiking, biking and other alpine activities.

If interested, please send resume, cover letter and the contact information of 3 references to mei.koh@utah.edu.